منابع مشابه
The PACE trial in chronic fatigue syndrome.
In their randomised trial of treatments for patients with chonic fatigue syndrome, Peter White and colleagues (March 5, p 823) defi ne a clinically useful diff erence between the means of the primary outcomes as “0·5 of the SD of these measures at baseline, equating to 2 points for Chalder fatigue questionnaire and 8 points for short form-36”. They cite achieving a mean clinically useful differ...
متن کاملPain in chronic fatigue syndrome: response to rehabilitative treatments in the PACE trial.
BACKGROUND Pain is a common symptom of chronic fatigue syndrome (CFS). We investigated the effects of the treatments used in the PACE trial [cognitive behavioural therapy (CBT), graded exercise therapy (GET), adaptive pacing therapy (APT) and specialist medical care (SMC)] on pain in CFS. METHOD We compared pain outcomes including individual painful symptoms, taken from the CDC criteria for C...
متن کاملHeterogeneity in chronic fatigue syndrome - empirically defined subgroups from the PACE trial.
BACKGROUND Chronic fatigue syndrome is likely to be a heterogeneous condition. Previous studies have empirically defined subgroups using combinations of clinical and biological variables. We aimed to explore the heterogeneity of chronic fatigue syndrome. METHOD We used baseline data from the PACE trial, which included 640 participants with chronic fatigue syndrome. Variable reduction, using a...
متن کاملRecovery from chronic fatigue syndrome after treatments given in the PACE trial
BACKGROUND A multi-centre, four-arm trial (the PACE trial) found that rehabilitative cognitive behaviour therapy (CBT) and graded exercise therapy (GET) were more effective treatments for chronic fatigue syndrome (CFS) than specialist medical care (SMC) alone, when each was added to SMC, and more effective than adaptive pacing therapy (APT) when added to SMC. In this study we compared how many ...
متن کاملThe planning, implementation and publication of a complex intervention trial for chronic fatigue syndrome: the PACE trial
The PACE trial was a four-arm trial of specialist medical care, compared with specialist medical care with a supplementary therapy: adaptive pacing therapy, cognitive-behavioural therapy or graded exercise therapy, for patients with chronic fatigue syndrome. The trial found that both cognitive-behavioural and graded exercise therapies were more effective than either of the other two treatments ...
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ژورنال
عنوان ژورنال: The Lancet
سال: 2011
ISSN: 0140-6736
DOI: 10.1016/s0140-6736(11)60682-x